Amlodipine and simvastatin interaction

amlodipine. Rationale: Drug‐drug interaction of simvastatin with amlodipine leads to an estimated 30% increase in the plasma concentration of simvastatin

Interaction between simvastatin and fenofibrate Concomitant administration of amlodipine and simvastatin caused a 1.6-fold increase in exposure of simvastatin

by YT Zhou 2024 Cited by 73simvastatin, lercanidipine–simvastatin, and amlodipine–atorvastatin); and 3) mutual interactions amlodipine–simvastatin interaction information. Since a dose

reported, but none with a simvastatin-amlodipine interaction. [16, 17] gerous interactions of some statins (simvastatin) with drugs.

by CG Park 2024 Cited by 34Non-concurrent dosing attenuates the pharmacokinetic interaction between amlodipine and simvastatin Interaction between amlodipine and simvastatin in patients

However, there is a drug interaction between simvastatin and amlodipine. Amlodipine can increase the concentration of simvastatin which

Istin (amlodipine) Co-administration of multiple doses of 10mg of amlodipine with 80mg simvastatin resulted in a 77% increase in exposure to simvastatin compared to simvastatin alone. Limit the dose of simvastatin to 20mg daily in patients on amlodipine. In clinical interaction studies, amlodipine did not affect the pharmacokinetics

Amlodipine can interact with several other medications. Different Taking amlodipine with simvastatin (Zocor) can cause the levels of simvastatin to

reported, but none with a simvastatin-amlodipine interaction. [16, 17] gerous interactions of some statins (simvastatin) with drugs.