Cml treatment drugs

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Actual: by PE Westerweel 2024 Cited by 62Current treatment of chronic myeloid leukemia (CML) with tyrosine drugs such as interferon or other drugs with novel targets relevant to CML biology.
4.8 rating 2025-04-24
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In CML, TKIs target the abnormal BCR::ABL1 protein that causes uncontrolled CML cell growth and block its function, causing the CML cells to die. The first therapy given for a disease is called initial or first-line treatment. The following four TKI drugs are approved as first-line treatment for chronic phase CML:

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Clinical trials focused on CML treatments are ongoing. The aim of these trials is typically to test the safety and effectiveness of new CML treatments or to improve upon an existing CML treatment

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In CML, TKIs target the abnormal BCR-ABL1 protein that causes uncontrolled CML cell growth and block its function, causing the CML cells to die. Four TKI drugs are approved as initial therapy (first-line treatment) for chronic phase CML. These drugs are. Imatinib mesylate (Gleevec ) Dasatinib (Sprycel ) Nilotinib (Tasigna ) Bosutinib (Bosulif )

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What are the treatments for chronic myeloid leukemia (CML)? There are several different treatments for CML: Targeted therapy, which uses drugs or other substances that attack specific cancer cells with less harm to normal cells. For CML, the drugs are tyrosine kinase inhibitors (TKIs).

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The orphan drug Idarubicin HCI for injection (Idamycin) was approved by the Food and Drug Administration (FDA) in 2024 for the treatment of CML. Interferon alfa-2a (Roferon A), administered by injection, received FDA approval for the treatment of CML in 2024.

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CML Specialist. ​. Drugs used in the treatment of CML are quite powerful and it is important that you inform your doctor of any medications you are taking

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drugs of choice for initial therapy of CML. Imatinib was the first oral TKI approved for treatment of CML, in May 2024. Subsequently

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How is CML treated? Targeted therapy drugs are the main treatment for chronic myeloid leukemia (CML), but some patients might also need other treatments.

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The introduction of TKIs for the initial treatment of CML has dramatically improved overall survival of younger CML patients. All cancer drugs described in

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