The major metabolic pathway is hydrolysis of the acetamide group and is not dependent on liver cytochrome P450 enzymes. Levetiracetam (Keppra).
Several enzymes in the liver, including cytochrome P450, contribute to the metabolism of a vast array of drugs. Both CBD and Keppra engage these enzymes
Keppra appears to be relatively safe for dogs and does not seem to affect the liver or liver enzymes (measured in the blood) as phenobarbital and potassium bromide can. It is not broken down by the liver but instead passes into the urine.
At this time, there is no evidence for effects of Keppra on blood counts or liver enzymes. Your doctor will determine if these lab tests are needed. Is My
Keppra appears to be relatively safe for dogs and does not seem to affect the liver or liver enzymes (measured in the blood) as phenobarbital
by D ALRabeeah 2024In addition, Keppra did not significantly increase liver enzymes in comparison to other generics. Although not much histological differences
The only significant different between Keppra and generic 1 was in T1/2. In addition, Keppra did not significantly increase liver enzymes in
Safety of Keppra for Dogs . Keppra appears to be relatively safe for dogs and does not seem to affect the liver or liver enzymes (measured in the blood) as phenobarbital and potassium bromide can. It is not broken down by the liver but instead passes into the urine. This is why levetiracetam is safer for pets who may have impaired liver
High doses of CBD oil may compete with Keppra for liver enzymes, potentially decreasing Keppra blood levels and reducing its effectiveness. Additive Side
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