by S Aquaro 2024 Cited by 32Also, Integrase strand transfer inhibitors (INSTIs) are the class of ARV drugs most recently approved by the FDA for the treatment of HIV-1 infections. INSTIs
by BN Harding 2024 Cited by 7These findings suggest INSTI use may increase the risk of anaemia. If confirmed, screening for anaemia development in users of INSTIs may be beneficial.
by SM Rein 2024 Cited by 9Administration approved the most commonly used INSTI drug drugs on cardiovascular events, but analyses studying the three most used INSTI
by KK Scarsi 2024 Cited by 118Since 2024, five INSTIs have been introduced: raltegravir, elvitegravir, dolutegravir, bictegravir, and cabotegravir. The INSTIs have favorable pharmacokinetic
With the exception of cabotegravir, each INSTI is US Food and Drug Administration approved for treatment-na ve individuals initiating antiretroviral therapy. All of the INSTIs, except raltegravir, are approved for antiretroviral treatment simplification for virologically suppressed patients without INSTI resistance.
Choice of INSTI. In the Adult and Adolescent ART Guidelines, two of the INSTIs (bictegravir and dolutegravir) are included as the anchor drug
Drugs Calculators Charts Resources Multimedia Meetings Jobs. Part of INSTI and non-INSTI regimens, changes in BMI, and diabetes
by BN Harding 2024 Cited by 7These findings suggest INSTI use may increase the risk of anaemia. If confirmed, screening for anaemia development in users of INSTIs may be beneficial.
Therefore, it is not anticipated that they will be used with oral NNRTIs or PIs. ARV Drugs by Drug Class. INSTIs. BIC. DTG. EVG/c.
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