Omeprazole, a moderate CYP2C19 inhibitor, reduces the pharmacological activity of Plavix. Avoid using omeprazole concomitantly or 12 hours apart with Plavix. Consider using another acid-reducing agent with less CYP2C19 inhibitory activity Plavix Prescribing Information. If possible, it is recommended to avoid taking Plavix and omeprazole together.
activity of PLAVIX than omeprazole (see DRUG INTERACTIONS and ACTION AND. CLINICAL PHARMACOLOGY). Gastrointestinal. Active GI lesions. PLAVIX
(Plavix) and its use when As such, the FDA recommends. against the concomitant use of Plavix (clopidogrel) and omeprazole because the co-administration.
The evidence for the interaction is so overwhelming, the FDA published labeling changes in the prescribing information for Plavix warning against taking it with omeprazole: Omeprazole, a moderate CYP2C19 inhibitor, reduces the pharmacological activity of Plavix.
Omeprazole, a moderate CYP2C19 inhibitor, reduces the pharmacological activity of Plavix. Avoid using omeprazole concomitantly or 12 hours apart with Plavix. Consider using another acid-reducing agent with less CYP2C19 inhibitory activity Plavix Prescribing Information. If possible, it is recommended to avoid taking Plavix and omeprazole together.
omeprazole or esomeprazole with Plavix. Omeprazole and COGENT Published: No Adverse Interaction Between Omeprazole, Clopidogrel.
Omeprazole, a moderate CYP2C19 inhibitor, reduces the pharmacological activity of Plavix. Avoid using omeprazole concomitantly or 12 hours apart with Plavix. Consider using another acid-reducing agent with less CYP2C19 inhibitory activity Plavix Prescribing Information. If possible, it is recommended to avoid taking Plavix and omeprazole together.
Omeprazole can reduce the effectiveness of Plavix, an antiplatelet drug, and increase the risk of cardiovascular events. Learn how omeprazole inhibits the liver enzyme CYP2C19 that transforms Plavix and what alternatives to consider.
Drug Interactions between omeprazole and Plavix. This report displays the potential drug interactions for the following 2 drugs: omeprazole; Plavix (clopidogrel); Edit list (add/remove drugs)
Hence Omeprazole being a much more expensive drug than it is now.....