Amiodarone increases the anticoagulant effect of Warfarin. Sucralfate potentially decreases the effects of Warfarin. Manufacturer advises separate administration
When warfarin is combined with alcohol, the effects of warfarin can be altered and may lead to a greater risk of bleeding or a decreased warfarin effect.
Phenytoin: There may be an initial increase in warfarin effect (due to altered binding), then a decrease in warfarin effect (due to increased
Please. Refer to Warfarin Interactions handbook12 for further list Numerous drugs interact with warfarin, either increasing or decreasing anticoagulant effect
, the following objectives will be covered: Describe warfarin's significant drug-drug interactions that will increase and decrease its effect.
Selected warfarin drug-drug interactions. Warfarin related Links. Decreased warfarin effect (Lower INR). Increased warfarin effect (POTENTIATION).
Medications that interfere with the effect of warfarin. This is a partial list of medications that may increase or decrease warfarin effect on the INR. The patient's medications should be analyzed closely for drug interactions with warfarin, especially when initiating or altering therapy.
Medications that interfere with the effect of warfarin. This is a partial list of medications that may increase or decrease warfarin effect on the INR. The patient's medications should be analyzed closely for drug interactions with warfarin, especially when initiating or altering therapy.
Generally, patients on warfarin should stop the warfarin 5 days before the operation. This will make sure that the effect of warfarin decreases prior to
Comments
You're correct that the effects don't decrease as more are used, and the effects are cumulative. But, for whatever reason, you should never use more than 5 drops at one time, even if the cumulative effect of the drops ends up being more than 5.