Clindamycin can be given in combination with another agent that covers anaerobes
Class. Name of Drug(s) Key Indications(s) Broadest activity of any antibiotic (does NOT cover MRSA, Mycoplasma, and some Pseudomonas) Clindamycin. Anaerobes
Yes: Clindamycin mainly covers anaerobic infections. These anaerobes are the bacteria that can reside in a patients mouth. Clindamycin can be used in aspiration pneumonias and in lung abscesses (a pocket full of pus in the lungs).
compared to clindamycin). Only covers anaerobes. use. Anaerobic coverage (e.g, metronidazole plus cefepime produces broad-spectrum coverage).
If MRSA coverage is required, doxycycline or Bactrim (trimethoprim-sulfamethoxazole) can be added. Clindamycin covers anaerobes, but it is
Antibiotics that Cover the Anaerobes (including Bacteroides fragilis) Imipenem, Meropenem, Doripenem, Clindamycin Moxifloxacin
Oral anaerobes are easily covered with penicillins or clindamycin – think Anything that a dentist would prescribe. Does double anaerobic
Clindamycin as Primary Therapy? . 73 . Cover gram positive, gram negative and anaerobe.
cephamycins: anaerobic coverage for many anaerobes in GIT → often Does not cover gram-negatives or anaerobes. High oral bioavailability (1:1 IV
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