Sulindac vs ibuprofen

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Actual: SULINDAC AND IBUPROFEN IN CIRRHOSIS 185 Discussion Sulindac is a unique NSAID because it is administered as an inactive pro-drug (sulindac 0.001 sulfoxide) that is reversibly converted to an active NS metabolite (sulindac sulfide), primarily in the liver 0.05 and possibly in the kidney (7,19).
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